Peyronie's disease is a condition in which scar tissue (plaque) develops inside the penis, causing curvature, pain, and sometimes difficulty with erections or sexual activity. Treatment options depend on the severity of symptoms and may include topical creams to help relieve discomfort, Trimix injections to improve erectile function when ED is also present, or Platelet-Rich Plasma (PRP) therapy, an emerging treatment that supports tissue healing.